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. 2017 May 29;8:307. doi: 10.3389/fphar.2017.00307

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Copyright © 2017 Hewitson, Holt, Tan, Wigg, Samuel and Smith.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Quantitative increase in histone marks during progressive fibrosis. Figures show the number of (A) H3K9Ac and (B) H3K9Me3 marks before (D0) and after 3 days (D3) and 10 days (D10) of UUO. Results are expressed as number of individual histone marks per 0.25 mm², with the average for each group shown with a bar. (C) DAPI staining was used to show the total DNA. n = 6 animals each group, ^∗p < 0.05 vs. respective D0.