Table 4. Cumulative Events Up to Three Years after the Nested Control Period.
Variables | Entire patients | Propensity score-matched patients | Hazard ratio (95% CI) | p value | ||||
---|---|---|---|---|---|---|---|---|
RAF (n=425) | CF (n=349) | p value | RAF (n=248) | CF (n=248) | p value | |||
Total death, n (%) | 7 (1.6) | 13 (3.7) | 0.070 | 4 (1.6) | 6 (2.4) | 0.523 | 0.66 (0.18–2.37) | 0.526 |
Cardiac death | 03 (0.7) | 06 (1.7) | 0.313 | 02 (0.8) | 03 (1.2) | NS | 0.66 (0.10–4.00) | 0.655 |
Non-cardiac death | 4 (0.9) | 7 (2.0) | 0.237 | 2 (0.8) | 3 (1.2) | NS | 0.66 (0.11–4.00) | 0.664 |
Myocardial infarction (MI) , n (%) | 10 (2.3) | 12 (3.4) | 0.366 | 04 (1.6) | 08 (3.2) | 0.242 | 0.49 (0.14–1.65) | 0.252 |
ST-segment elevation MI | 4 (0.9) | 5 (1.4) | 0.738 | 1 (0.4) | 3 (1.2) | 0.623 | 0.33 (0.03–3.20) | 0.339 |
Non-ST-segment elevation MI | 06 (1.4) | 07 (2.0) | 0.522 | 03 (1.2) | 05 (2.0) | 0.724 | 0.59 (0.14–2.51) | 0.722 |
Revascularizations, n (%) | 80 (18.8) | 17 (4.8) | <0.001 | 53 (21.3) | 14 (5.6) | <0.001 | 4.54 (2.44–8.43) | <0.001 |
TLR | 44 (10.3) | 15 (4.2) | 0.002 | 27 (10.8) | 12 (4.8) | 0.012 | 2.40 (1.18–4.85) | 0.015 |
TVR | 57 (13.4) | 15 (4.2) | <0.001 | 36 (14.5) | 12 (4.8) | <0.001 | 3.33 (1.69–6.58) | 0.001 |
Non-TVR | 29 (6.8) | 04 (1.1) | <0.001 | 21 (8.4) | 04 (1.6) | <0.001 | 5.64 (1.90–16.6) | 0.002 |
Stent thrombosis, n (%) | 6 (1.4) | 4 (1.1) | NS | 2 (0.8) | 4 (1.6) | 0.686 | 0.49 (0.09–2.73) | 0.421 |
Late | 03 (0.7) | 00 (0.0) | 02 (0.8) | 00 (0.0) | ||||
Very late | 3 (0.7) | 4 (1.1) | 0 (0.0) | 4 (1.6) | ||||
TLR MACE, n (%) | 47 (11.0) | 22 (6.3) | 0.021 | 29 (11.6) | 15 (6.0) | 0.027 | 2.05 (1.07–3.94) | 0.030 |
TVR MACE, n (%) | 65 (15.2) | 29 (8.3) | 0.003 | 40 (16.1) | 18 (7.2) | 0.002 | 2.45 (1.36–4.41) | 0.003 |
Total MACE, n (%) | 86 (20.2) | 31 (8.8) | <0.001 | 56 (22.5) | 20 (8.0) | <0.001 | 3.32 (1.92–5.73) | <0.001 |
Follow-up, day | 1088±55 | 1076±10 | 0.039 | 1087±63 | 1082±89 | 0.442 |
RAF, routine angiographic follow-up; CF, clinical follow-up; MACE, major adverse cardiovascular events; TLR, target lesion revascularization; TVR, target vessel revascularization; CI, confidence interval; NS, not significant (>0.999).
Values are numbers and percentages. The p value for categorical data from chi-square test or Cox-proportional hazard models.