Fig. 3. Changes in eGFR by CKD-EPI (A) or MDRD (B), and SCr (C). Change in eGFR by CKD-EPI or MDRD and SCr level in first-line tenofovir-backbone ART and ART-naïve groups in a retrospective cohort. Symbols in each line indicate median value. ^*p<0.05 by Mann-Whitney U test. eGFR, estimated glomerular filtration rate; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; MDRD, Modification of Diet in Renal Disease; SCr, serum creatinine; ART, antiretroviral therapy; TDF, tenofovir disoproxil fumarate.