Figure 3.

Representative maximum likelihood tree constructed from a 1031 nucleotide position alignment of 17 WO minor capsid protein gene sequence. The tree (historically used for WO classification) includes sequences from all the WOs used in Figure 1, as well as two additional WO sequences (from WOPip1 and WOPip5), the genomes of which lack integrase/recombinase genes (Kent et al., 2011a). The gene sequences of WOPip1 and WOPip5 are highlighted with blue boxing. Minor capsid gene sequences originating from WOs with the group 1 serine replication recombinase module (sr1RRM) referred to in the main text are indicated, as are their integration sites (labeled as in Figure 1). The serine recombinase-based phylogenetic classification of these WOs is also highlighted, using branch tip suffixes written in red (sr1–sr3). The bootstrap support for two monophyletic groups containing WO sequence representatives with varying integrase/recombinase gene sequences is also shown. The minor capsid protein sequences alignment is provided in Supplementary File 4.