Figure 2.

Association of the seropositivity against each of the studied H. pylori proteins with the risk of colorectal cancer among H. pylori seropositive participants (positive for four or more H. pylori proteins), overall and by tumor site. ORs from multinomial logistic regression mixed model adjusted by age, sex, education, family history of colorectal cancer, and smoking status; province included as a random-effect term. Statistically significant associations are highlighted in black. Analyses based on 2,476 controls, 1,467 colorectal, 395 right colon, 500 left colon, and 550 rectal cancer cases with complete information for all the covariates.