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. 2017 May 24;10(4):491–500. doi: 10.1016/j.tranon.2017.04.002

Figure 1.

Figure 1

Effect of Chk1 inhibitors on cellular radiosensitivity. Cellular radiosensitivity was examined using a clonogenic survival assay. (A) After X-irradiation, EMT6 cells were treated with either 5 nM UCN-01 (▲) or 200 nM MK-8776 (○) and incubated for 7 days. (B) After X-irradiation, HeLa cells were treated with either 10 nM UCN-01 (▲) or 500 nM MK-8776 (○) and incubated for 14 days. The surviving fraction was calculated using a correction for plating efficiency without X-irradiation. Data are expressed as means ± S.D. from three experiments.