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Schematic of atopic dermatitis (AD) induction and CWPS treatment. To induce AD-like symptoms, the hair-removed dorsal skin and ear of BALB/c mice (n = 6) were sensitized with 2% DNCB. The dorsal skin and ear of mice of re-challenged with 0.5% DNCB at the indicated time. CWPS dissolved in distilled water was orally administrated to BALB/c mice daily from day 1. The mice were sacrificed on day 13 to evaluate the effects of DNCB and CWPS treatment.
