Table 7.
Pathological changes of focal cerebral ischemia reperfusion in rats.
| Group | n | Dose (mg/kg) | − | + | ++ | +++ |
|---|---|---|---|---|---|---|
| Sham operation group | 16 | 11 | 1 | 0 | 0 | |
| Model group | 10 | 0 | 0 | 0 | 1 | 9 |
| Nimodipine group | 11 | 20 | 0 | 0 | 5 | 6 |
| Cerebral collateral group | 12 | 500 | 2 | 3 | 2 | 5 |
| Large dose group of the Rabdosia rubescens total flavonoids | 12 | 200 | 8 | 4 | 0 | 0 |
| Middle dose group of the Rabdosia rubescens total flavonoids | 12 | 100 | 8 | 4 | 0 | |
| Small dose group of the Rabdosia rubescens total flavonoids | 11 | 50 | 1 | 4 | 6 | 0 |
“−” with normal nerve cells, glial cells were basically normal; “+” a few nerve cell degeneration, glial cells were normal; “++” most of the neural cells degeneration, with normal glial cells or partial condensation; “+++” all nerve cell degeneration, glial cell condensation or disappear. According to semi quantitative standards experimental animals in each group were measured.