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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Gynecol Oncol. 2017 Feb 22;145(3):453–461. doi: 10.1016/j.ygyno.2017.02.028

Figure 2. ALT-803 mediates proliferation of NK cells from ascites of ovarian cancer patients.

Figure 2

PBMCs from healthy donors or ascites cells from ovarian cancer patients were labeled with CellTrace Violet dye and placed in culture for 1 week with media alone (NT), 1 nM ALT-803 (ALT) or 1 nM IL-15. Cells were then harvested and stained for surface antigens. (A) Representative histograms showing CellTrace dilution on healthy PBNK or patient ASC NK treated with ALT-803. (B) Pooled data showing proliferation (% cells that have diluted dye) on PBNK and ASC NK. Circles and squares represent different individuals within groups (n = 5 for PBNK and n =7 for ASC NK). One-way ANOVA was used to calculate statistics within the PBNK and ASC NK groups.