A. thaliana |
Promoters and gene bodies[77] |
Loss of MET1 (DNA methyltransferase) |
|
C. neoformans |
Sub-telomeres |
Loss of Ccc1 (chromodomain protein in PRC2 complex) |
|
N. crassa |
Sub-telomeres and interspersed genic regions |
Loss of DIM-2 (DNA methyltransferase)
Loss of DIM-5 (H3K9 methyltransferase) or HP1
|
Normal H3K27me2/3
H3K27me lost or reduced at normal regions and gained at centromeres and other regions normally bound by HP1 [38,40]
|
C. elegans |
Alternating H3K27me3 and H3K36me3 domains on autosomes |
Loss of MES-4 (H3K36 methyltransferase) |
|
M. musculus (mesenchymal progenitor cells) |
Promoters and gene bodies |
H3.3K36M or depletion of Nsd1/2 and Setd2 (H3K36 methyltransferases) |
|
M. musculus (neural stem cells) |
Promoters and gene bodies |
DNMT3a KO (DNA methyltransferase) |
|
M. musculus (embryonic fibroblasts) |
Promoters and gene bodies |
DNMT1n/n (DNA methyltransferase hypomorph) |
|