Table 2.
Odds ratio (95% Confidence Interval) between dietary fiber and WOMAC pain sub-groups among eligible participants regardless status of radiographic OA at baseline
| Dietary Fiber | Odds Ratio (95% CI)2 | |||||||
|---|---|---|---|---|---|---|---|---|
| Q1 (lowest) (n=2239)1 | Q2 (n=2231) | Q3 (n=2236) | Q4 (highest) (n=2234) | Q2 vs. Q1 | Q3 vs. Q1 | Q4 vs. Q1 | P for trend | |
| Pain patterns | Total fiber (g/day) | |||||||
| No pain, n (%) | 719 (32.1) | 754 (33.8) | 807 (36.2) | 851 (38.1) | 1.0 | 1.0 | 1.0 | |
| Mild pain, n (%) | 846 (37.8) | 937 (42.0) | 863 (38.6) | 907 (40.6) | 1.16 (0.97,1.39) | 0.92 (0.77,1.10) | 1.05 (0.88,1.26) | 0.92 |
| Moderate pain, n (%) | 488 (21.8) | 433 (19.4) | 434 (19.4) | 380 (17.0) | 0.92 (0.75,1.13) | 0.85 (0.70,1.04) | 0.76 (0.61,0.93) | 0.006 |
| Severe pain, n (%) | 186 (8.3) | 107 (4.8) | 132 (5.9) | 96 (4.3) | 0.65 (0.48,0.89) | 0.79 (0.59,1.07) | 0.56 (0.41,0.78) | 0.002 |
| Cereal grain fiber (g/day) | ||||||||
| No pain, n (%) | 734 (32.8) | 745 (33.4) | 785 (35.1) | 867 (38.8) | 1.0 | 1.0 | 1.0 | |
| Mild pain, n (%) | 840 (37.5) | 910 (40.8) | 912 (40.8) | 889 (39.8) | 1.10 (0.92,1.31) | 1.00 (0.84,1.20) | 0.99 (0.83,1.18) | 0.49 |
| Moderate pain, n (%) | 481 (21.5) | 428 (19.2) | 436 (19.5) | 391 (17.5) | 0.89 (0.73,1.10) | 0.93 (0.76,1.13) | 0.85 (0.70,1.04) | 0.09 |
| Severe pain, n (%) | 184 (8.2) | 147 (6.6) | 103 (4.6) | 87 (3.9) | 0.95 (0.71,1.28) | 0.70 (0.51,0.97) | 0.55 (0.39,0.79) | 0.0002 |
| Fruit and vegetable fiber (g/day) | ||||||||
| No pain, n (%) | 750 (33.5) | 779 (34.9) | 783 (35.0) | 818 (36.6) | 1.0 | 1.0 | 1.0 | |
| Mild pain, n (%) | 873 (39.0) | 906 (40.6) | 901 (40.3) | 876 (39.2) | 1.10 (0.92,1.31) | 1.14 (0.95,1.36) | 1.01 (0.84,1.21) | 0.96 |
| Moderate pain, n (%) | 463 (20.7) | 431 (19.3) | 432 (19.3) | 411 (18.4) | 0.91 (0.75,1.12) | 0.98 (0.80,1.20) | 0.80 (0.66,0.99) | 0.05 |
| Severe pain, n (%) | 152 (6.8) | 116 (5.2) | 121 (5.4) | 130 (5.8) | 0.92 (0.67,1.27) | 1.02 (0.74,1.40) | 0.84 (0.61,1.15) | 0.30 |
| Legume and nut fiber (g/day) | ||||||||
| No pain, n (%) | 752 (33.6) | 796 (35.7) | 785 (35.1) | 800 (35.8) | 1.0 | 1.0 | 1.0 | |
| Mild pain, n (%) | 862 (38.5) | 890 (39.9) | 879 (39.3) | 923 (41.3) | 0.98 (0.82,1.17) | 1.02 (0.85,1.22) | 1.09 (0.92,1.30) | 0.21 |
| Moderate pain, n (%) | 448 (20.0) | 440 (19.7) | 443 (19.9) | 404 (18.1) | 0.92 (0.75,1.12) | 0.99 (0.81,1.22) | 0.87 (0.70,1.07) | 0.26 |
| Severe pain, n (%) | 177 (7.9) | 105 (4.7) | 130 (5.8) | 107 (4.8) | 0.63 (0.46,0.87) | 0.86 (0.63,1.16) | 0.75 (0.55,1.03) | 0.29 |
1
n for number of knees;
2
Model adjusted for age (years), sex (men vs. women), race (white vs. non-white), education level (below vs. college or above), tobacco use (never, former, current smokers), total calorie intake (kcal), physical activity (PASE, continuous), baseline radiographic OA status (yes vs. no), and NSAIDs use (yes vs. no).