Table 3.
Odds ratio (95% Confidence Interval) between dietary fiber and WOMAC pain trajectories among those with radiographic OA at baseline
| Dietary Fiber | Odds Ratio2 | |||||||
|---|---|---|---|---|---|---|---|---|
| Q1 (lowest) (n=9761) | Q2 (n=929) | Q3 (n=920) | Q4 (highest) (n=878) | Q2 vs. Q1 | Q3 vs. Q1 | Q4 vs. Q1 | P for trend | |
| Pain sub-groups | Total fiber (g/day) | |||||||
| No pain, n (%) | 221 (22.6) | 248 (26.7) | 264 (28.7) | 268 (30.5) | 1.00 | 1.00 | 1.00 | |
| Mild pain, n (%) | 378 (38.7) | 374 (40.3) | 346 (37.6) | 369 (42.0) | 0.88 (0.66,1.17) | 0.76 (0.58,1.01) | 0.87 (0.65,1.16) | 0.28 |
| Moderate pain, n (%) | 269 (27.6) | 240 (25.8) | 240 (26.1) | 189 (21.5) | 0.76 (0.57,1.02) | 0.70 (0.52,0.94) | 0.57 (0.42,0.77) | 0.0004 |
| Severe pain, n (%) | 108 (11.1) | 67 (7.2) | 70 (7.6) | 53 (6.0) | 0.59 (0.38,0.90) | 0.61 (0.39,0.93) | 0.41 (0.24,0.68) | 0.0006 |
| Cereal grain fiber (g/day) | ||||||||
| No pain, n (%) | 252 (25.8) | 223 (24.0) | 259 (28.1) | 268 (30.5) | 1.00 | 1.00 | 1.00 | |
| Mild pain, n (%) | 366 (37.5) | 388 (41.8) | 376 (40.9) | 335 (38.2) | 1.28 (0.96,1.69) | 1.00 (0.76,1.31) | 1.01 (0.77,1.33) | 0.6 |
| Moderate pain, n (%) | 257 (26.3) | 234 (25.2) | 221 (24.0) | 227 (25.8) | 1.08 (0.80,1.45) | 0.91 (0.68,1.22) | 0.98 (0.73,1.32) | 0.59 |
| Severe pain, n (%) | 102 (10.4) | 84 (9.0) | 64 (7.0) | 48 (5.5) | 1.04 (0.69,1.57) | 0.65 (0.41,1.03) | 0.55 (0.33,0.91) | 0.006 |
| Fruit and vegetable fiber (g/day) | ||||||||
| No pain, n (%) | 247 (25.3) | 244 (26.3) | 239 (26.0) | 267 (30.4) | 1.00 | 1.00 | 1.00 | |
| Mild pain, n (%) | 367 (37.6) | 369 (39.7) | 384 (41.7) | 345 (39.3) | 1.13 (0.84,1.51) | 1.17 (0.88,1.56) | 0.90 (0.68,1.20) | 0.35 |
| Moderate pain, n (%) | 268 (27.5) | 243 (26.2) | 230 (25.0) | 199 (22.7) | 0.93 (0.69,1.25) | 0.85 (0.63,1.15) | 0.60 (0.45,0.81) | 0.0004 |
| Severe pain, n (%) | 94 (9.6) | 72 (7.8) | 67 (7.3) | 67 (7.6) | 0.89 (0.57,1.39) | 0.85 (0.55,1.33) | 0.61 (0.39,0.95) | 0.02 |
| Legume and nut fiber (g/day) | ||||||||
| No pain, n (%) | 247 (25.3) | 242 (26.0) | 269 (29.2) | 243 (27.7) | 1.00 | 1.00 | 1.00 | |
| Mild pain, n (%) | 380 (38.9) | 382 (41.1) | 334 (36.3) | 371 (42.2) | 1.03 (0.78,1.36) | 0.88 (0.67,1.17) | 1.09 (0.83,1.44) | 0.57 |
| Moderate pain, n (%) | 245 (25.1) | 242 (26.1) | 245 (26.6) | 208 (23.7) | 0.98 (0.73,1.32) | 0.92 (0.69,1.23) | 0.77 (0.57,1.05) | 0.09 |
| Severe pain, n (%) | 104 (10.7) | 63 (6.8) | 73 (7.9) | 56 (6.4) | 0.60 (0.38,0.94) | 0.70 (0.46,1.09) | 0.69 (0.44,1.09) | 0.23 |
1
n for number of knees;
2
Model adjusted for age (years), sex (men vs. women), race (white vs. non-white), education level (below vs. college or above), tobacco use (never, former, current smokers), total calorie intake (kcal), physical activity (PASE, continuous), and NSAIDs use (yes vs. no).