Table 1.
General characteristics of dementia cohort by antipsychotic use
General characteristics of study cohort | Exposed to antipsychotic medication (n = 3735) | Not exposed to antipsychotic medication (n = 5939) | % Difference (95% CI) |
---|---|---|---|
Female | 66.2% (2474) | 67.8% (4025) | 1.5* (0–3.4) |
Mean age at diagnosis of dementia (years) | 82.4 (6.8) | 82.5 (6.8) | 0.1 (−0.1 to 0.4) |
History of | |||
Epilepsy | 2.7% (99) | 2.3% (138) | 0.3 (−0.3 to 1.0) |
Parkinsonism | 4.0% (149) | 3.7% (222) | 0.25 (−0.5 to 1.1) |
Atrial fibrillation | 14.6% (546) | 15.4% (914) | 0.7 (−2.2 to 0.7) |
Venous thromboembolism | 5.8% (217) | 5.5% (329) | 0.27 (−0.6 to 1.2) |
Diabetes | 13.7% (511) | 15.8% (941) | 2.2* (0.7–3.6) |
Ischaemic heart disease | 23.9% (893) | 23.2% (1377) | 0.7 (−1.0 to 2.5) |
Cerebrovascular disease | 22.3% (832) | 22.5% (1338) | 0.25 (−2.0 to 1.5) |
Hip fracture | 6.5% (243) | 6.1% (364) | 0.4 (−0.6 to 1.4) |
* Significant difference between the group exposed to antipsychotic medication and the group not exposed
Values in table are presented as the percentage with the number (of people) in parenthesis, with the exception of Mean age at diagnosis which is presented as the mean age with the standard deviation in parenthesis