Table 2.

Adjusted mortality hazard ratios by exposure to antipsychotic medication

Time to	Exposed to antipsychotic medication			Not exposed to antipsychotic medication			Adjusted HR Model 1 (95% CI)a	Adjusted HR Model 2 (95% CI)b
	Events	Follow-up years	Rate per 100 person-years (95% CI)	Events	Follow-up years	Rate per 100 person-years (95% CI)
All older people with all-cause dementia (n = 9674)	2342	100.9	23.2 (22.2–24.2)	2777	121.9	22.8 (22.0–23.6)	1.0 (0.96–1.09)	1.06 (0.99–1.13)
Older people with Alzheimer’s disease (n = 6996)	1689	74.0	22.8 (22.2–23.9)	2006	90.2	22.2 (21.2–23.2)	1.02 (0.96–1.09)	1.06 (0.99–1.14)
Older people with all-cause dementia known to primary care only (n = 5089)	1122	37.7	29.8 (28.1–31.6)	1834	61.0	30.0 (28.7–31.5)	1.0 (0.91–1.10)	1.03 (0.96–1.10)

CI Confidence interval, HR hazard ratio

^aModel 1 = adjusted for history of medical co-morbidities as listed in Table 1, age at dementia diagnosis and gender

^bModel 2 = adjusted for history of medical co-morbidities as listed in Table 1, age at dementia diagnosis, gender, and exposure to anxiolytic and/or hypnotic medication