Table 3. Comparison between Never-Smoker and Ever-Smoker Group Regarding QCT and PFT.
| Never-Smoker (n = 119) | Ever-Smoker (n = 45) | P | |
|---|---|---|---|
| FVC (% predicted) | 102.8 ± 13.7 | 92.6 ± 11.2 | < 0.001 |
| FEV1 (% predicted) | 112.0 ± 18.7 | 97.8 ± 12.7 | < 0.001 |
| FEV1/FVC (%) | 79.9 ± 5.5 | 77.5 ± 8.5 | 0.089 |
| FEF25–75% (% predicted) | 97.0 ± 30.6 | 88.8 ± 24.9 | 0.110 |
| TLC (% predicted) | 109.2 ± 22.3 | 108.6 ± 16.1 | 0.947 |
| VC (% predicted) | 110.1 ± 24.4 | 95.8 ± 20.5 | 0.112 |
| RV (% predicted) | 104.9 ± 46.4 | 117.9 ± 40.5 | 0.441 |
| DLco (% predicted) | 92.5 ± 17.6 | 96.7 ± 16.0 | 0.500 |
| TLCCT, mL | 3993.0 ± 1001.6 | 5254.4 ± 870.8 | < 0.001 |
| FRCCT, mL | 2649.8 ± 703.5 | 3189.9 ± 841.8 | < 0.001 |
| %LAAI-950 | 1.4 ± 3.2 | 1.3 ± 2.3 | 0.864 |
| %LAAE-856 | 16.8 ± 16.3 | 16.9 ± 13.4 | 0.956 |
| HU 15 percentile-inspiration | −895.4 ± 26.3 | −907.3 ± 16.2 | 0.007 |
| MLA (HU) | |||
| Inspiration | −827.9 ± 31.7 | −841.2 ± 19.5 | 0.013 |
| Expiration | −752.9 ± 45.5 | −746.8 ± 48.4 | 0.467 |
| Pi10 | |||
| Inspiration | 4.1 ± 0.2 | 4.3 ± 0.3 | < 0.001 |
| Expiration | 4.2 ± 0.3 | 4.3 ± 0.3 | 0.012 |
| Skewness | |||
| Inspiration | 2.4 ± 0.4 | 2.5 ± 0.3 | 0.586 |
| Expiration | 1.5 ± 0.5 | 1.3 ± 0.5 | 0.132 |
| Kurtosis | |||
| Inspiration | 4.9 ± 2.0 | 5.0 ± 1.8 | 0.728 |
| Expiration | 1.1 ± 1.6 | 0.7 ± 1.3 | 0.163 |
DLco = diffusion capacity of lung for carbon monoxide, FEF25–75% = forced expiratory flow between 25–75%, FEV1 = forced expiratory volume in 1 second, FRCCT = functional residual capacity, FVC = forced expiratory vital capacity, HU = Hounsfield unit, MLA = mean lung attenuation, PFT = pulmonary function test, Pi10 = inner perimeter of 10 mm, QCT = quantitative computed tomography, RV = residual volume, TLC = total lung capacity, VC = vital capacity, %LAAE-856 = percentage of low attenuation area with CT attenuation values less than −856 HU at expiration, %LAAI-950 = percentage of low attenuation area with CT attenuation values less than −950 HU at inspiration