Table 4. Comparisons of QCT and PFT Measurements Grouped by Smoking Intensity.
| ≤ 20 Pack Years (n = 21) | > 20 Pack Years (n = 15) | P | |
|---|---|---|---|
| FVC (% predicted) | 92.1 ± 9.5 | 94.4 ± 12.1 | 0.533 |
| FEV1 (% predicted) | 96.3 ± 13.2 | 98.3 ± 12.7 | 0.644 |
| FEV1/FVC (%) | 77.6 ± 11.4 | 75.7 ± 4.5 | 0.536 |
| FEF25–75% (% predicted) | 91.9 ± 28.3 | 79.5 ± 17.7 | 0.146 |
| TLC (% predicted) | 102.2 ± 8.1 | 110.5 ± 24.6 | 0.495 |
| VC (% predicted) | 93.6 ± 8.7 | 84.0 ± 15.7 | 0.278 |
| RV (% predicted) | 112.6 ± 28.3 | 127.3 ± 63.1 | 0.653 |
| DLco (% predicted) | 99.2 ± 14.0 | 89.3 ± 19.0 | 0.366 |
| TLCCT, mL | 5565.6 ± 963.5 | 5272.9 ± 450.9 | 0.317 |
| FRCCT, mL | 3310.5 ± 704.3 | 3392.8 ± 993.9 | 0.779 |
| %LAAI-950 | 1.7 ± 2.8 | 1.4 ± 2.2 | 0.720 |
| %LAAE-856 | 17.2 ± 12.3 | 20.6 ± 15.6 | 0.487 |
| HU 15 percentile-inspiration | -911.5 ± 16.0 | -907.2 ± 18.5 | 0.488 |
| MLA (HU) | |||
| Inspiration | -846.2 ± 18.1 | -839.9 ± 24.1 | 0.406 |
| Expiration | -752.0 ± 44.2 | -754.5 ± 55.6 | 0.882 |
| Pi10 | |||
| Inspiration | 4.3 ± 0.3 | 4.3 ± 0.3 | 0.806 |
| Expiration | 4.3 ± 0.3 | 4.3 ± 0.3 | 0.985 |
| Skewness | |||
| Inspiration | 2.4 ± 0.4 | 2.4 ± 0.3 | 0.988 |
| Expiration | 1.4 ± 1.5 | 1.5 ± 1.6 | 0.547 |
| Kurtosis | |||
| Inspiration | 5.0 ± 2.0 | 5.0 ± 1.8 | 0.995 |
| Expiration | 0.7 ± 1.1 | 1.1 ± 1.6 | 0.352 |
DLco = diffusion capacity of lung for carbon monoxide, FEF25–75% = forced expiratory flow between 25–75%, FEV1 = forced expiratory volume in 1 second, FRCCT = functional residual capacity, FVC = forced expiratory vital capacity, HU = Hounsfield unit, MLA = mean lung attenuation, PFT = pulmonary function test, Pi10 = inner perimeter of 10 mm, QCT = quantitative computed tomography, RV = residual volume, TLC = total lung capacity, VC = vital capacity, %LAAE-856 = percentage of low attenuation area with CT attenuation values less than −856 HU at expiration, %LAAI-950 = percentage of low attenuation area with CT attenuation values less than −950 HU at inspiration