Table 6. Correlation between FEV1/FVC and QCT Parameters.
All Subjects (n = 164) | Ever-Smokers (n = 45) | Never-Smokers (n = 119) | ||||
---|---|---|---|---|---|---|
FEV1/FVC | P | FEV1/FVC | P | FEV1/FVC | P | |
TLCCT | −0.184 | 0.330 | −0.387 | 0.014 | −0.326 | < 0.001 |
%LAAI-950 | −0.133 | 0.483 | −0.248 | 0.122 | −0.182 | 0.052 |
HU 15 percentile-inspiration | 0.107 | 0.573 | 0.275 | 0.086 | 0.293 | 0.001 |
MLA-inspiration | 0.081 | 0.671 | 0.249 | 0.122 | 0.277 | 0.003 |
Pi10-inspiration | −0.452 | 0.012 | −0.455 | 0.003 | −0.083 | 0.380 |
FEV1 = forced expiratory volume in 1 second, FVC = forced expiratory vital capacity, HU = Hounsfield unit, MLA = mean lung attenuation, Pi10 = inner perimeter of 10 mm, QCT = quantitative computed tomography, TLC = total lung capacity, %LAAI-950 = percentage of low attenuation area with CT attenuation values less than −950 HU at inspiration.