Supplementary Table 2.
Subgroup multiple logistic regression analysis of dysnatremia as independent risk factors for hospital mortality in model 1.
| Subgroup | Hyponatremia§ | Hypernatremia§ | Mixed dysnatremia§ | |||
|---|---|---|---|---|---|---|
| OR (95%CI) | P value | OR (95%CI) | P value | OR (95%CI) | P value | |
| Age, year | ||||||
| ≤65 | 2.722 (2.034–3.643) | 0.000 | 18.350 (12.853–26.198) | 0.000 | 21.886 (11.753–40.755) | 0.000 |
| <65 | 2.075 (1.653–2.606) | 0.000 | 11.112 (8.440–14.631) | 0.000 | 24.623 (16.162–37.513) | 0.000 |
| Gender | ||||||
| Male | 1.963 (1.575–2.447) | 0.000 | 14.659 (11.014–19.512) | 0.000 | 21.475 (13.748–33.544) | 0.000 |
| Female | 2.860 (2.090–3.913) | 0.000 | 11.952 (8.231–17.353) | 0.000 | 27.276 (15.320–48.564) | 0.000 |
| BMI, kg/m2 | ||||||
| <18.5 | 1.534 (0.453–5.198) | 0.492 | 71.139 (12.345–409.950) | 0.000 | 1233.153 (38.420–39580.284) | 0.000 |
| 18.5–24.99 | 2.297 (1.906–2.769) | 0.000 | 13.003 (10.241–16.509) | 0.000 | 20.950 (14.578–30.105) | 0.000 |
| ≥25 | 1.689 (0.632–4.513) | 0.296 | 7.195 (2.006–25.806) | 0.002 | 32.104 (2.952–349.133) | 0.004 |
| Underlying diseases | ||||||
| Cancer | 1.635 (1.069–2.502) | 0.023 | 11.942 (6.105–23.359) | 0.000 | 26.998 (9.615–75.806) | 0.000 |
| Pulmonary | 3.062 (2.010–4.633) | 0.000 | 6.266 (3.353–11.710) | 0.000 | 25.139 (7.850–80.503) | 0.000 |
| Cardiovascular | 4.863 (3.203–7.385) | 0.000 | 9.117 (5.037–16.502) | 0.000 | 9.550 (2.855–31.946) | 0.000 |
| Digestive | 1.445 (0.726–2.877) | 0.295 | 11.231 (3.914–32.232) | 0.000 | 53.383 (13.800–206.493) | 0.000 |
| Hematological | 3.398 (2.103–5.490) | 0.000 | 8.980 (3.723–21.660) | 0.000 | 48.642 (8.840–267.664) | 0.000 |
| Neurological | 2.199 (1.038–4.658) | 0.040 | 16.821 (8.191–34.544) | 0.000 | 23.310 (7.966–68.207) | 0.000 |
| Urinary and renal | 1.390 (0.746–2.588) | 0.300 | 17.257 (8.551–34.826) | 0.000 | 33.917 (7.819–147.114) | 0.000 |
| Cardiothoracic surgery | 2.385 (1.065–5.340) | 0.035 | 27.029 (12.388–58.976) | 0.000 | 18.501 (6.336–54.021) | 0.000 |
| General surgery | 2.282 (1.056–4.931) | 0.036 | 6.568 (2.299–18.763) | 0.000 | 8.285 (1.500–45.761) | 0.003 |
| Others | 2.321 (10.22–5.273) | 0.044 | 11.917 (4.531–31.341) | 0.000 | 77.078 (16.156–367.723) | 0.000 |
| AKI | ||||||
| Yes | 1.810 (1.411–2.322) | 0.000 | 10.784 (8.161–14.252) | 0.000 | 11.053 (7.502–16.285) | 0.000 |
| No | 1.526 (1.157–2.013) | 0.003 | 4.596 (2.817–7.499) | 0.000 | 16.996 (6.574–43.944) | 0.000 |
| Length of hospital stay, day | ||||||
| ≤30 | 1.627 (1.323–2.001) | 0.000 | 14.168 (11.042–18.179) | 0.000 | 18.563 (11.980–28.763) | 0.000 |
| >30 | 2.928 (1.879–4.561) | 0.000 | 5.233 (2.926–9.360) | 0.000 | 9.789 (5.116–18.730) | 0.000 |
§
Normonatremia as the reference.
BMI – body mass index; AKI – acute kidney injury; OR – odds ratio; CI – confidence interval.