Supplementary Table 4.
Subgroup multiple logistic regression analysis of dysnatremia as independent risk factors for hospital mortality in model 3.
| Subgroup | Improved hyponatremia | Persistent hyponatremia | Improved hypernatremia | Persistent hypernatremia | ||||
|---|---|---|---|---|---|---|---|---|
| OR(95%CI) | P | OR(95%CI) | P | OR(95%CI) | P | OR(95%CI) | P | |
| Age, year | ||||||||
| ≤65 | 2.887 (2.113–3.945) | 0.000 | 12.639 (7.705–20.731) | 0.000 | 25.364 (16.541–38.893) | 0.000 | 21.923 11.773–40.825) | 0.000 |
| >65 | 1.644 (1.264–2.138) | 0.000 | 4.827 (3.166–7.359) | 0.000 | 20.010 (14.552–27.516) | 0.000 | 24.275 (15.899–37.066) | 0.000 |
| Gender | ||||||||
| Male | 1.779 (1.394–2.271) | 0.000 | 7.318 (4.819–11.113) | 0.000 | 26.151 (18.611–36.745) | 0.000 | 21.742 (13.914–33.974) | 0.000 |
| Female | 2.555 (1.794–3.639) | 0.000 | 6.448 (3.781–10.996) | 0.000 | 19.409 (12.602–29.891) | 0.000 | 27.078 (15.178–48.307) | 0.000 |
| BMI, kg/m2 | ||||||||
| <18.5 | 1.931 (0.472–7.894) | 0.360 | 20.986 (14.599–30.168) | 0.000 | 55.895 (8.888–351.535) | 0.000 | 1209.328 (37.744–38746.89) | 0.000 |
| 18.5–24.99 | 2.093 (1.701–2.576) | 0.000 | 6.28 (4.43–8.902) | 0.000 | 22.766 (17.252–30.042) | 0.000 | 20.986 (14.599–30.168) | 0.000 |
| ≥25 | 1.777 (0.559–5.648) | 0.330 | 5.025 (0.587–42.991) | 0.140 | 8.816 (1.948–39.891) | 0.005 | 32.095 (2.959–348.159) | 0.004 |
| Underlying diseases | ||||||||
| Cancer | 1.184 (0.731–1.916) | 0.492 | 11.343 (5.09–25.277) | 0.000 | 13.494 (4.684–38.876) | 0.000 | 25.983 (9.194–73.434) | 0.000 |
| Pulmonary | 3.416 (2.139–5.456) | 0.000 | 0.962 (0.288–3.214) | 0.949 | 16.5 (8.103–33.597) | 0.000 | 25.592 (7.866–83.263) | 0.000 |
| Cardiovascular | 4.409 (2.724–7.137) | 0.000 | 5.893 (2.519–13.789) | 0.000 | 13.128 (6.396–26.943) | 0.000 | 9.585 (2.866–32.059) | 0.000 |
| Digestive | 1.44 (0.699–2.963) | 0.323 | 3.019 (0.329–27.677) | 0.328 | 16.053 (5.374–47.952) | 0.000 | 50.959 (13.174–197.116) | 0.000 |
| Hematological | 2.78 (1.571–4.918) | 0.000 | 29.114 (7.417–114.275) | 0.000 | 3.738 (1.076–12.978) | 0.038 | 37.481 (7.029–199.851) | 0.000 |
| Neurological | 1.492 (0.598–3.722) | 0.391 | 8.002 (3.076–20.817) | 0.000 | 47.75 (20.678–110.263) | 0.000 | 28.754 (9.403–87.927) | 0.000 |
| Urinary and renal | 1.67 (0.829–3.364) | 0.152 | 4.526 (0.977–20.973) | 0.054 | 24.442 (11.571–51.631) | 0.000 | 32.258 (7.501–138.731) | 0.000 |
| Cardiothoracic surgery | 0.936 (0.304–2.882) | 0.909 | 10.885 (4.104–28.867) | 0.000 | 79.21 (32.91–190.65) | 0.000 | 18.084 (6.162–53.07) | 0.000 |
| General surgery | 2.279 (0.966–5.377) | 0.060 | 3.499 (0.86–14.233) | 0.080 | 15.866 (4.211–59.776) | 0.000 | 8.242 (1.487–45.693) | 0.016 |
| Others | 3.978 (1.902–8.317) | 0.000 | 2.31 (0.425–12.545) | 0.332 | 29.003 (10.267–81.93) | 0.000 | 122.536 (27.544–545.138) | 0.000 |
| AKI | ||||||||
| Yes | 1.915 (1.457–2.518) | 0.000 | 4.893 (3.387–7.068) | 0.000 | 25.307 (18.021–35.538) | 0.000 | 10.927 (7.422–16.087) | 0.000 |
| No | 1.247 (0.911–1.706) | 0.168 | 1.656 (0.591–4.643) | 0.337 | 7.438 (4.331–12.774) | 0.000 | 17.028 (6.573–44.108) | 0.000 |
| Length of hospital stay, day | ||||||||
| ≤30 | 1.507 (1.197–1.898) | 0.000 | 7.109 (4.89–10.337) | 0.000 | 22.685 (16.984–30.299) | 0.000 | 18.657 (12.039–28.914) | 0.000 |
| >30 | 3.514 (2.166–5.703) | 0.000 | 2.823 (1.411–5.651) | 0.003 | 25.407 (10.435–61.859) | 0.000 | 9.913 (5.18–18.973) | 0.000 |
§
Normonatremia as the reference.
BMI – body mass index; AKI – acute kidney injury; OR – odds ratio; CI – confidence interval.