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. 2017 May 30;10:160. doi: 10.3389/fnmol.2017.00160

Figure 1.

Figure 1

miR-193b-3p is downregulated in the mouse model of amyotrophic lateral sclerosis (ALS). (A) qRT-PCR results show the miRNA levels of miR-193b-3p in the spinal cord of SOD1G93A mutants compared with controls (~90 days). The results were averages of eight pairs of littermate mice. Data represent the mean ± standard error of the mean (SEM). *P < 0.05 vs. controls. (B,C) qRT-PCR results show the miRNA levels of miR-193b-3p in NSC-34 cells transfected with miR-193b-3p mimics, inhibitors or scrambled sequence. The results were averages of four independent experiments. Data represent the mean ± SEM. ***P < 0.001 vs. controls.