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. 2017 May 30;10:160. doi: 10.3389/fnmol.2017.00160

Figure 6.

Figure 6

Model. Schematic representation highlighting the role of miR-193b-3p in the development of ALS. miR-193b-3p directly targets TSC1 to regulate mTORC1 activity. Inhibition of miR-193b-3p leads to TSC1 increase and mTORC1 inactivation, resulting in enhanced autophagy.