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. 2017 May 30;11:308. doi: 10.3389/fnins.2017.00308

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Copyright © 2017 Guillebaud, Girardet, Abysique, Gaigé, Barbouche, Verneuil, Jean, Leprince, Tonon, Dallaporta, Lebrun and Troadec.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Acute 4th ventricle endozepine administration modifies food intake. Food intake measured at different time intervals after treatment (A) and cumulative food intake (B) monitored over 9 h after central injection of either saline (vehicle), ODN or OP (2 μg/rat). Animals were fasted 18 h before the 4th ventricle injection, and food was presented 45 min after treatment. ^*, ^#P < 0.05; ^**, ^##P < 0.01 and ^***, ^###P < 0.001 significantly different from vehicle-treated animals, respectively for ODN and OP-treated rats.