. Author manuscript; available in PMC: 2018 Jun 1.

Published in final edited form as: Pulm Pharmacol Ther. 2017 Mar 16;44:88–95. doi: 10.1016/j.pupt.2017.03.006

Table 1.

V_{max app.} and K_{m app.} for Ac-CoA at different concentrations of inhibitor MG149. V_{max app.}, hill slope and k_half for histone H4 peptide at different concentrations of inhibitor MG149. Data shown are representative of 3 independent experiments ± SD.

[MG149] (µM)	Ac-CoA		Histone H4 peptide
	V_{max app.} (pmol/min)	K_{m app.} (µM)	V_{max app.} (pmol/min)	Hill slope	K_half (µM)
0	12 ± 1.2	4.1 ± 1.1	10 ± 0.3	2.1 ± 0.3	43
80	9.1 ± 1.0	4.0 ± 1.1	10 ± 0.4	2.5 ± 0.4	50
160	6.0 ± 0.3	1.8 ± 0.3	9.8 ± 0.3	4.2 ± 0.7	64
240	4.0 ± 0.3	1.6 ± 0.4	10 ± 0.3	4.0 ± 0.6	84