Table II.

Comparison to the state-of-the-art MEA systems

Reference	[19]	[6]	[21]	[22]	This work
Type	In-pixel Amp	In-pixel Amp	In-pixel Amp	Switch Matrix	Switch Matrix
Technology	0.5 μm	0.13 μm	0.18 μm	0.35 μm	0.18 μm
Active Area	2.28×1.14 mm2	9 pixel groups of 0.128 mm2	1×1 mm2/2x2 mm2	3.85×2.10 mm2	4.48×2.43 mm2
No. Transducers	32768	144	4225 / 1024	26400	59760
No. Different Measurement Modes	1	4	1	1	5
Pixel Pitch	8.775 μm	89.4 / 357.8 μmd	16 / 32 μm	17.5 μm	13.5 μm
Transducers/mm2	12987	125 / 7.8	977, 3906	3265	5487
No. Voltage Readout Channels	32768	144	4225	1024	2048 AP + 32 LFP
A/D Conversion	128 pipeline	Off chip	Off chip	1024 single-slope	32 + 4 SAR
ADC Resolution	9 bit	-	-	10 bit	10 bit
Sampling Rate	2.4 kS/sa	-	77 (25) kS/sa	20 kS/s	20 kS/s
Input-referred Noise	-	12.7 μVrmse	44 μVrmsb	2.4 μVrmsb,c	2.4 μVrmsb,c
Total Power	4 W	-	-	75 mW	86 mW
Die Size	9.5×9.5 mm2	2.2×2 mm2	-	10.1×7.6 mm2	12×8.9 mm2

^aWhen reading out all channels.

^bNoise integration over 300Hz-10kHz.

^cIncluding ADC.

^dEquivalent square-shaped pixel dimension, for the same spatial density.

^eNoise integration over 0.5Hz-10kHz.