Table 1.
Average values (SD) for demographic variables and cognitive performance at baseline.
| mAD (n = 22) | aMCI (n = 23) | HE (n = 25) | All | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Arm A (n = 14) | Arm B (n = 8) | Χ2/U | p | Arm A (n = 10) | Arm B (n = 13) | Χ2/U | p | Arm A (n = 12) | Arm B (n = 13) | Χ2/U | p | Χ2/H | p | |
| Sex (male/female) | 5/9 | 3/5 | 0.007 | 0.993 | 7/3 | 7/6 | 0.619 | 0.431 | 4/8 | 3/10 | 0.326 | 0.568 | 5.673 | 0.059 |
| Education (year) | 9.6 (3.7) | 10.1 (3.2) | 50 | 0.714 | 10.7 (3.1) | 12.2 (4) | 50 | 0.376 | 11.2 (4.2) | 11 (4.2) | 79 | 1 | 2.63 | 0.268 |
| Age (year) | 76.4 (6) | 73.9 (4.7) | 64 | 0.616 | 71.4 (6.6) | 72.8 (5.7) | 53 | 0.446 | 69.9 (5.6) | 71 (6.8) | 70 | 0.650 | 7.15 | 0.028 |
| Memory (z) | −2 (0.5) | −1.6 (0.63) | 30 | 0.082 | −0.67 (0.65) | −0.87 (0.67) | 73 | 0.648 | 0.44 (0.93) | 0.18 (0.96) | 89 | 0.547 | 42.98 | <0.001 |
| Attention (z) | −0.87 (1.25) | −0.10 (1.05) | 38 | 0.238 | 0.76 (0.78) | 0.71 (0.73) | 72 | 0.693 | 1.05 (0.43) | 1.36 (0.36) | 47 | 0.098 | 28.02 | <0.001 |
| EF (z) | −0.27 (0.89) | −0.79 (1.03) | 70 | 0.365 | 0.15 (0.75) | −0.03 (0.86) | 73 | 0.648 | 0.57 (0.61) | 0.61 (0.52) | 84 | 0.769 | 15.95 | <0.001 |
Abbreviations: SD = standard deviation; HE = healthy elderly; aMCI = amnestic mild cognitive impairment subjects; mAD = mild Alzheimer’s Disease patients; EF = executive functions; p = 2-sided probability value; U = test statistic of Mann–Whitney U test comparing the two arms A vs. B; H = test statistic of Kruskal–Wallis test comparing the three groups; z = z-scores calculated on published normative data of the same age and education sample.