Table 3.

Analysis of DMN functional connectivity at baseline and comparing ΔCT vs. ΔAC.

Contrast	Sample	H	Region	Cluster (voxel)	t	FWE_corr p Cluster	MNI Coordinates
							x	y	z
Baseline	aMCI > HE	L	Postcentral gyrus	360	4.98	0.014	−34	−20	40
		L	PCu	1253	4.63	<0.001	−2	−46	50
		R	PCu		4.62		10	−60	34
	mAD < aMCI	L	PCu	610	4.79	<0.001	−4	−70	28
		R	PCu		3.97		10	−62	28
ΔCT > ΔAC	ALL groups	R	PCu	288	4.22	0.033	14	−64	48
ΔCT < ΔAC	mAD	L	MTL	302	5.21	0.026	−28	−42	−4
INT	aMCI (ΔCT < ΔAC) > HE (ΔCT < ΔAC)	R	mSFG	288	4.56	0.033	2	46	44
		L	mSFG		3.93		−8	50	30

Abbreviations: H = hemisphere; L = left; R = right; CT = cognitive training; AC = active control condition; HE = healthy elderly; aMCI = Mild Cognitive Impairment; mAD = mild Alzheimer’s Disease; mSFG = medial superior frontal gyrus; PCu = precuneus; MTL = medial temporal lobe.