Figure 1.
The simplified mesocorticolimbic pathway in the rodent brain. Solid black lines represent dopaminergic projection; dashed blue lines represent GABAergic projections and dotted red lines represent glutamatergic projections. Regions in green are implicated in the drug craving, blue in binge, and red in the withdrawal stages of the addiction cycle. PFC = prefrontal cortex; Hipp = hippocampus; CPu = caudate and putamen; NAc = nucleus accumbens; AMG = amygdala; VTA = ventral tegmental area.