Table 1.
Univariate analysis of risk factors for anastomotic leakage in patients treated with laparoscopic rectal cancer surgery without diverting stoma (n = 736).
| Variables | Number of anastomotic leakage/total patients (%) | P |
|---|---|---|
| Sex | 0.002 | |
| Female | 12/272 (4.4) | |
| Male | 53/464 (11.4) | |
| Age, yr | 0.999 | |
| ≥70 | 29/330 (8.8) | |
| <70 | 36/406 (8.9) | |
| BMI (kg/m2) | 0.839 | |
| <25 | 46/507 (9.1) | |
| ≥25 | 19/229 (8.3) | |
| ASA score | <0.001 | |
| 1 | 14/280 (7.8) | |
| 2 | 41/517 (7.9) | |
| 3 | 10/39 (25.6) | |
| AJCC stage | 0.163 | |
| 0-II | 33/439 (7.5) | |
| II/IV | 32/297 (10.8) | |
| Maximum tumor size (cm) | 0.896 | |
| <4 | 24/320 (7.5) | |
| ≥4 | 29/416 (7.0) | |
| Location of tumor | 0.005 | |
| Upper | 25/447 (5.6) | |
| Mid | 16/215 (7.4) | |
| Low | 12/74 (16.2) | |
| Operative time (min) | 0.003 | |
| <240 | 37/624 (5.9) | |
| ≥240 | 16/112 (14.3) | |
| Transfusion | <0.001 | |
| No | 41/674 (6.1) | |
| Yes | 12/62 (19.4) | |
| Neoadjuvant chemoradiation | 0.051 | |
| No | 42/651 (6.5) | |
| Yes | 11/85 (12.9) | |
| Number of linear stapler firing | 0.061 | |
| <2 | 20/376 (5.3) | |
| ≥2 | 33/360 (9.2) | |
AJCC: American Joint Committee on Cancer; ASA: American Society of Anesthesiologists, BMI: body mass index.