Table 1.

Examples of molecules subject to glucuronidation in mammals

IBD is inflammatory bowel disease.

Aglycone	Aglycone's effect	Disease/health	Refs.
Endogenous
Arachidonic acid	Signaling molecule	Inflammation	48
Bilirubin	Neurotoxin, antioxidant	Gall stones, jaundice	19
Chenodeoxycholate	Digestion	Cholestasis	89
Chondroitin sulfate	Glycosaminoglycan	Cancer	90
Dopamine	GI motility, water absorption	IBD, constipation	5
Estradiol	Sex hormone, development	Breast cancer	26
Hyaluronic acid	Glycosaminoglycan	Cancer	10
Norepinephrine	GI motility	IBD	5
Serotonin	GI motility	IBD	40
Testosterone	Sex hormone	Prostate cancer	32
Thyroxine	Thyroid regulation	Metabolic disorder	36
Exogenous
AOM	Alkylating agent	Cancer	66
Belinostat	HDAC inhibitor	GI toxicity	57
Benzo[a]pyrene	DNA adduct formation	Cancer	70
Diclofenac	NSAID	GI toxicity	62
Ethanol	Depressant	Liver toxicity	91
Indomethacin	NSAID	GI toxicity	64
Ketoprofen	NSAID	GI toxicity	62
Nicotine	Stimulant	Addiction	75
Panobinostat	HDAC inhibitor	GI toxicity	58
PhIP	Alkylating agent	Cancer	69
SN-38	Topoisomerase I inhibitor	GI toxicity	54