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. 2017 Apr 5;292(21):8605–8615. doi: 10.1074/jbc.M117.780924

Table 1.

The details of mRHDV infection assay

Groups Animal Number Pathogen Dosagea Method Clinical signs Dead
ml
1 Rabbit 3 mRHDV 1 Intramuscular injection + + + 3/3 (100%)
2 Rabbit 3 RHDV (JX/CHA/97) 1 Intramuscular injection + + + 3/3 (100%)
3 Rabbit 3 PBS 1 Intramuscular injection − − − 0/3 (0)
4 Mouse 5 mRHDV 0.1 Intramuscular injection − − − − − 0/5 (0)
5 Mouse 5 RHDV (JX/CHA/97) 0.1 Intramuscular injection − − − − − 0/5 (0)
6 Mouse 5 PBS 0.1 Intramuscular injection − − − − − 0/5 (0)

a mRHDV, 1 × 104.3 TCID50/ml; RHDV (JX/CHA/97), 1 × 103 LD50/ml. +, positive; −, negative.