Figure 7.

ATP1B2 is highly expressed in most regions of the CNS from late embryonic stages to adulthood. A, ATP1B2 was detectable from late embryonic stages (E18.5) with levels increasing until P10–P20, after which high levels were maintained into adulthood. B, ATP1B2 was expressed at high levels in all brain regions tested, except for the olfactory lobe and the pituitary gland. Trace amounts of ATP1B2 were present in the olfactory lobe, but levels were below the detection limit in the pituitary. Blots were performed using two independent sets of tissue samples. For each tissue sample, a minimum of three separate blots were run with identical results.