Figure 7.

TNF-α-evoked NF-κB expression in HUVECs transfected with a luciferase-expressing NF-κB promotor is decreased by ZNE treatment in a concentration-dependent manner. Values represented are mean ± SEM of % promotor units recorded upon treatment with the corresponding vehicle control (n = 3 replicates). Statistical significance was tested with ANOVA followed by Tuckey's post-hoc test. ∗ denotes P < 0.05 compared to that of the expression evoked by TNF-α in the absence of ZNE, while # denotes P < 0.05 compared to that of the expression observed upon treatment with the vehicle control.