Fig. 4.

In vivo photothermal therapy with Lipo@HRP&ABTS. (A and B) IR thermal images (A) and tumor temperature change curves (B) of 4T1 tumor-bearing mice after i.v. injection of Lipo@HRP, Lipo@ABTS, or Lipo@HRP&ABTS under the 808-nm laser irradiation (+L, 0.8 W/cm² for 10 min). (C) H&E-stained tumor slices collected from mice at the following day after different treatments. (D) The tumor growth curves of different groups of mice after various treatments indicated (five mice per group). (E and F) IR thermal images (E) and temperature changes (F) of SLNs without (upper row) or with (lower row) metastases on mice with local injection of Lipo@HRP&ABTS into mouse legs under 808-nm laser irradiation (0.8 W/cm² for 5 min).