Table 1.
Comparison among IgG4 reactivities of BmR1, Ov-BmR1 and Ll-BmR1 using a panel of serum samples from patients with various parasitic infections and healthy controls (endemic and non-endemic normals). BmR1 is the antigen expressed by Bm17DIII DNA sequence; while Ov-BmR1 and Ll-BmR1 are the antigens expressed by the homologs of Bm17DIII DNA sequence in O. volvulus and L. loa respectively.
| Serum type | No | Positive by BmR1 (%) | Positive by Ov-BmR1 and Ll-BmR1 (%) |
| O. volvulus, mf positive | 70 | 1 (1.43) | 1 (1.43) |
| L. loa, mf positive | 14 | 6 (42.86) | 6 (42.86) |
| W. bancrofti, mf positive | 33 | 8 (24.24) | 8 (24.24) |
| B. malayi, mf positive | 28 | 28 (100) | 28 (100) |
| Trichuris trichiura | 8 | 0 | 0 |
| Ascaris lumbricoides | 8 | 0 | 0 |
| Mixed infection with T. trichuris, A. lumbricoides and hookworm | 8 | 0 | 0 |
| Entamoeba histolytica (invasive) | 11 | 0 | 0 |
| Toxocara | 14 | 0 | 0 |
| Gnathostoma spinigerum | 1 | 0 | 0 |
| Strongyloides stercoralis | 6 | 0 | 0 |
| Endemic normals (healthy controls) | 29 | 0 | 0 |
| Non-endemic normals (healthy controls) | 32 | 0 | 0 |
| TOTAL | 262 |