Table 2.
Results of ELISAs to detect IgG1, IgG2 and IgG3 anti-filarial antibodies in serum samples from patients with various helminthiasis and healthy controls (non-endemic normals) using BmR1, Ov-BmR1 and Ll-BmR1. All antigens (tested separately) demonstrated identical results with all serum samples.
Type of serum sample | Number of positive results out of number of samples tested | ||
IgG1-ELISA | IgG2-ELISA | IgG3-ELISA | |
O. volvulus mf+ | 47/47 | 0/21 | 0/21 |
L. loa mf+ | 14/14 | 0/14 | 0/14 |
W. bancrofti mf+ | 6/6 | 0/6 | 0/6 |
W. bancrofti chronic | 6/6 | 0/6 | 0/6 |
B. malayi mf+ | 10/10 | 0/10 | 0/10 |
B. malayi chronic | 14/14 | 0/14 | 0/14 |
Soil-transmitted helminth infections | 10/10 | 0/10 | 0/10 |
Non-endemic normals (healthy controls) | 10/10 | 0/10 | 0/10 |