Table 2.

Annual incidence of pediatric persistent PAH, US MarketScan Data, 2010–2013.

	Cases (n)	Children- years	Incidence per 1,000,000 children-years (95% CI)
2010
Total	54	8,595,453	6.3 (4.7–8.2)
Age (years)
<1	30	273,872	109.5 (73.9–156.4)
1 - < 2	18	429,984	41.9 (24.8–66.2)
2 - < 6	2	1,832,981	1.1 (0.1–3.9)
6 - < 12	1	2,931,260	0.3 (0–1.9)
12 - < 18	3	3,127,356	1.0 (0.2–2.8)
Type of PAH
Idiopathic	4	8,595,453	0.5 (0.1–1.2)
Non-idiopathic	50	8,595,453	5.8 (4.3–7.7)
2011
Total	79	9,699,243	8.1 (6.5–10.2)
Age (years)
<1	31	314,670	98.5 (66.9–139.8)
1 - < 2	24	482,674	49.7 (31.9–74.0)
2 - < 6	7	2,065,065	3.4 (1.4–7.0)
6 - < 12	7	3,296,302	2.1 (0.9–4.4)
12 - < 18	10	3,540,531	2.8 (1.4–5.2)
Type of PAH
Idiopathic	8	9,699,243	0.8 (0.4–1.6)
Non-idiopathic	71	9,699,243	7.3 (5.7–9.2)
2012
Total	57	9,134,430	6.2 (4.7–8.1)
Age (years)
<1	25	307,789	81.2 (52.6–119.9)
1 - < 2	19	477,784	39.8 (23.9–62.1)
2 - < 6	2	1,957,535	1.0 (0.1–3.7)
6 - < 12	4	3,065,386	1.3 (0.4–3.3)
12 - < 18	7	3,325,936	2.1 (0.8–4.3)
Type of PAH
Idiopathic	8	9,134,430	0.9 (0.4–1.7)
Non-idiopathic	49	9,134,430	5.4 (4.0–7.1)
2013
Total	29	5,990,915	4.8 (3.2–7.0)
Age (years)
<1	11	232,034	47.4 (23.6–84.8)
1 - < 2	12	349,614	34.3 (17.7–60.0)
2 - < 6	1	1,296,013	0.8 (0.01–4.3)
6 - < 12	1	1,952,385	0.5 (0.01–2.9)
12 - < 18	4	2,160,870	1.9 (0.5–4.7)
Type of PAH
Idiopathic	3	5,990,915	0.5 (0.1–1.5)
Non-idiopathic	26	5,990,915	4.3 (2.8–6.4)