Table 4.
Principal components analysis.
| Factor | Description | Metabolites within factor |
|---|---|---|
| 1 | Medium-chain acylcarnitines | C8, C10, C12, C14:1, C14, C16:2, C16:1, C14:2, C12:1, C10:1 |
| 2 | Long-chain dicarboxyl-acylcarnitines | C20:1-OH/C18:1-DC, C18-OH/C16-DC, C20-OH/C18-DC, C16-OH/C14-DC, C18:1-OH/C16:1-DC, C20, C12-OH/ C10-DC, C14-OH/C12-DC |
| 3 | Short-chain dicarboxyl-acylcarnitines | C5-DC, C6:1-DC/C8:1-OH, C8:1-DC, C6-DC, Ci4-DC/C4-DC, C10-OH/C8-DC, C12-OH/C10-DC, Cit |
| 4 | Long-chain acylcarnitines | C18:1, C18:2, C18, C16, C20:4, C16:1-OH/C14:1-DC |
| 5 | Ketone-related | KET, HBUT, C4-OH, C2, Ala |
| 6 | Medium-chain acylcarnitines | C10:3, C8:1, C10:2, C10:1 |
| 7 | Branched-chain amino acids | Phe, Tyr, Leu/Ile, Val, Met |
| 8 | Urea cycle amino acids | Gly, Met, Ser, Orn, Arg, C5:1, Pro |
| 9 | Short-chain acylcarnitines | C4/Ci4, C3, C5’s |
| 10 | Malonyl carnitine, Aspartate | C5-OH/C3-DC, Asx |
| 11 | Histidine, 3-Hydroxy-linoleylcarnitine, Arginine, Tiglyl-carnitine | His, C18:2-OH, Arg, C5:1 |
| 12 | Glutamate, Valine | Glx, Val |
| 13 | Alanine, Proline, Non-esterified Fatty acids | Ala, Pro, NEFA |
| 14 | Docosanoyl-carnitine | C22 |
Included in the table are 12 factors identified from PCA. Column 2 lists the overall description of the factor, column 3 the individual metabolites comprising that factor. ALA, alanine; ARG, arginine; ASX, aspartic acid/asparagine; CIT, citrulline; GLX, glutamine/glutamate; GLY, glycine; HBUT, beta-hydroxybutyrate; HIS, histidine; KET, ketones; LEU/ILE, leucine/isoleucine; MET, methionine; NEFA, non-esterified fatty acids; ORN, ornithine; PHE, phenylalanine; PRO, proline; SER, serine; TYR, tyrosine; VAL, valine.