Table 3.
Median intake (g) | No. of subjects | Person years | Colorectal cancer | Colon cancer | Rectal cancer | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
No. of cases | RR† | 95% CI | No. of cases | RR† | 95% CI | No. of cases | RR† | 95% CI | ||||
Total meat‡ | ||||||||||||
Q1 | 26 | 4094 | 56 142 | 97 | 1.00 | Reference | 73 | 1.00 | Reference | 24 | 1.00 | Reference |
Q2 | 48 | 4093 | 55 387 | 101 | 1.12 | 0.84–1.49 | 72 | 1.04 | 0.74–1.45 | 29 | 1.35 | 0.78–2.34 |
Q3 | 64 | 4094 | 56 520 | 75 | 0.94 | 0.69–1.29 | 54 | 0.88 | 0.61–1.28 | 21 | 1.13 | 0.61–2.07 |
Q4 | 93 | 4093 | 58 632 | 70 | 1.01 | 0.74–1.40 | 45 | 0.88 | 0.60–1.30 | 25 | 1.43 | 0.80–2.56 |
Trend P | 0.48 | 0.33 | 0.80 | |||||||||
Red meat‡ | ||||||||||||
Q1 | 12 | 4094 | 55 685 | 98 | 1.00 | Reference | 68 | 1.00 | Reference | 30 | 1.00 | Reference |
Q2 | 23 | 4093 | 55 271 | 97 | 1.07 | 0.80–1.42 | 77 | 1.21 | 0.86–1.69 | 20 | 0.75 | 0.42–1.33 |
Q3 | 32 | 4094 | 57 089 | 69 | 0.86 | 0.62–1.18 | 42 | 0.75 | 0.50–1.12 | 27 | 1.10 | 0.64–1.89 |
Q4 | 49 | 4093 | 58 636 | 79 | 1.07 | 0.79–1.46 | 57 | 1.13 | 0.79–1.64 | 22 | 0.95 | 0.54–1.68 |
Trend P | 0.98 | 0.99 | 0.97 | |||||||||
Processed meat‡ | ||||||||||||
Q1 | 3 | 4094 | 56 692 | 100 | 1.00 | Reference | 74 | 1.00 | Reference | 26 | 1.00 | Reference |
Q2 | 8 | 4093 | 56 261 | 88 | 0.96 | 0.71–1.28 | 61 | 0.88 | 0.62–1.25 | 27 | 1.17 | 0.68–2.03 |
Q3 | 11 | 4094 | 55 763 | 81 | 0.98 | 0.72–1.34 | 63 | 1.00 | 0.70–1.44 | 18 | 0.90 | 0.48–1.69 |
Q4 | 19 | 4093 | 57 965 | 74 | 1.12 | 0.82–1.55 | 46 | 0.95 | 0.64–1.40 | 28 | 1.62 | 0.92–2.84 |
Trend P | 0.95 | 0.25 | 0.10 | |||||||||
Excluding cases within 2 years | ||||||||||||
Total meat‡ | ||||||||||||
Q1 | 26 | 4087 | 56 176 | 87 | 1.00 | Reference | 66 | 1.00 | Reference | 21 | 1.00 | Reference |
Q2 | 48 | 4087 | 55 452 | 89 | 1.09 | 0.80–1.47 | 61 | 0.97 | 0.68–1.39 | 28 | 1.46 | 0.82–2.59 |
Q3 | 64 | 4087 | 56 479 | 71 | 0.97 | 0.70–1.35 | 51 | 0.91 | 0.62–1.33 | 20 | 1.19 | 0.63–2.25 |
Q4 | 93 | 4086 | 58 540 | 69 | 1.09 | 0.78–1.51 | 44 | 0.93 | 0.62–1.38 | 25 | 1.59 | 0.87–2.91 |
Trend P | 0.73 | 0.46 | 0.60 | |||||||||
Red meat‡ | ||||||||||||
Q1 | 12 | 4087 | 55 707 | 89 | 1.00 | Reference | 62 | 1.00 | Reference | 27 | 1.00 | Reference |
Q2 | 23 | 4087 | 55 326 | 86 | 1.03 | 0.76–1.39 | 66 | 1.13 | 0.79–1.61 | 20 | 0.81 | 0.45–1.46 |
Q3 | 32 | 4087 | 57 044 | 65 | 0.87 | 0.62–1.21 | 40 | 0.77 | 0.51–1.16 | 25 | 1.10 | 0.62–1.93 |
Q4 | 49 | 4086 | 58 569 | 76 | 1.10 | 0.80–1.51 | 54 | 1.14 | 0.78–1.67 | 22 | 1.02 | 0.57–1.84 |
Trend P | 0.83 | 0.90 | 0.79 | |||||||||
Processed meat‡ | ||||||||||||
Q1 | 3 | 4087 | 56 698 | 92 | 1.00 | Reference | 68 | 1.00 | Reference | 24 | 1.00 | Reference |
Q2 | 8 | 4087 | 56 310 | 78 | 0.91 | 0.67–1.25 | 54 | 0.85 | 0.59–1.23 | 24 | 1.10 | 0.62–1.96 |
Q3 | 11 | 4087 | 55 750 | 74 | 0.95 | 0.69–1.32 | 56 | 0.96 | 0.65–1.40 | 18 | 0.94 | 0.50–1.79 |
Q4 | 19 | 4086 | 57 888 | 72 | 1.15 | 0.83–1.60 | 44 | 0.96 | 0.64–1.44 | 28 | 1.70 | 0.95–3.03 |
Trend P | 0.85 | 0.31 | 0.062 |
†Estimated hazard ratio after adjustments for age, height (quartiles), body mass index (quartiles), physical activity score, smoking status (never, past, current smoker), education years (≤8, 9–11, 12–14, ≥15 years), history of aspirin use (yes, no), alcohol consumption (g/day), menopausal status (premenopausal, postmenopausal), the intakes (quartiles) of total fiber, calcium, and vitamin D. ‡Meat consumption was adjusted for total energy intake by Willet method.