Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Apr 24;108(5):1071–1079. doi: 10.1111/cas.13213

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PMC Copyright notice

(a) BACH2 was detected in BACH2‐transfected FL‐18‐EB cells (FL‐18‐EB [BTB and CNC homology 2 (BACH2)+]) by PCR. (b) Phosphorylated transforming growth factor‐β‐activated kinase 1 (pTAK1) expression was downregulated in FL‐18‐EB (BACH2+) cells as shown by Western blot analysis. (c) p65 expression was downregulated in nuclear fractions of FL‐18‐EB (BACH2+) cells compared to FL‐18‐EB and FL‐18‐EB (control vector) cells. (d) The ratio of BACH2 expression level to LaminB1 is shown. (e) Immunohistochemistry in BACH2‐negative diffuse large B‐cell lymphoma (DLBCL) shows p65 positivity in the nucleus, pTAK1 positivity, and EBV‐encoded small RNA in situ hybridization (EBER (ISH)) positivity. (f) Immunohistochemistry in BACH2‐positive DLBCL shows p65 positivity in the cytoplasm, pTAK1 negativity, and EBER (ISH) negativity. (g) Immunohistochemistry in BACH2‐negative DLBCL shows nuclear staining of p50 and p52. (h) Immunohistochemistry in BACH2‐positive DLBCL shows cytoplasmic staining of p50 and p52.