Table 2.
Differential BTB and CNC homology 2 (BACH2) expression in Epstein–Barr virus (EBV)‐positive and EBV‐negative diffuse large B‐cell lymphoma (DLBCL) and EBV‐positive and EBV‐negative DLBCL, activated B‐cell‐like (ABC) type (b)
| Diagnosis | BACH2 expression | P‐value | |
|---|---|---|---|
| Positive | Negative | ||
| (a) | |||
| EBV‐positive DLBCL (n = 23) | 5 | 18 | <0.0001 |
| EBV‐negative DLBCL (n = 43) | 38 | 5 | |
| (b) | |||
| EBV‐positive DLBCL, ABC type (n = 15) | 3 | 12 | <0.0001 |
| EBV‐negative DLBCL, ABC type (n = 22) | 20 | 2 | |
According to the criteria reported by Kikuchi et al.,21 all five BACH2‐positive cases of EBV‐positive DLBCL were strongly positive for BACH2. Among 38 BACH2‐positive cases of EBV‐negative DLBCL, 10 cases were weakly positive and 28 cases were strongly positive for BACH2.