Figure 2.
Development of pancreatic cancer‐targeting oncolytic virus by a library approach. The pancreatic cancer‐targeting sequence is combined with a survivin promoter‐driven oncolytic adenovirus (AdSur‐SYE). Locally advanced pancreatic cancer is surgically unresectable but can be accessed by ultrasound‐ or computed tomography‐guided percutaneous injection or endoscopic ultrasound‐guided injection of viruses.