Table S5.
The association of THBG and clinical indexes of subjects
| Variables | Univariate correlation | |
|---|---|---|
| Pearson correlation | ||
| Age, years | r=0.246 | P=0.022* |
| BMI, kg/m2 | r=−0.048 | P=0.662 |
| Smoking history, pack-years | r=0.082 | P=0.453 |
| Smoking cessation duration, years | r=0.087 | P=0.426 |
| FEV1, %pred | r=−0.559 | P=0.000** |
| RV/TLC, %pred | r=0.464 | P=0.000** |
| RV, %pred | r=0.381 | P=0.000** |
| LAA, % | r=0.446 | P=0.000** |
| Spearman correlation | ||
| Hypertension | r=−0.149 | P=0.171 |
| Diabetes mellitus | r=−0.082 | P=0.451 |
| Abnormal TT3 | None | None |
| Abnormal FT3 | r=0.034 | P=0.755 |
| Abnormal TT4 | r=0.152 | P=0.163 |
| Abnormal FT4 | None | None |
| Abnormal TSH | r=−0.068 | P=0.536 |
Notes:
*
P<0.05 or
**
P<0.01: the variable was correlated with THBG levels. Pearson coefficient reflected the association of continuous variables with THBG, and Spearman coefficient reflected the association of categorical variables with THBG.
Abbreviations: BMI, body mass index; FEV1, forced expiratory volume in 1 s; LAA, low-attenuation area; RV, residual volume; THBG, thyroxine-binding globulin; TLC, total lung capacity; TT3, total T3; FT3, free T3; TT4, total T4; FT4, free T4; TSH, thyroid-stimulating hormone; pred, predicted.