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. 2017 May 30;12(5):e0178404. doi: 10.1371/journal.pone.0178404

Fig 1. Comparisons of plasma levels of HMGB1 and sRAGE measured by ELISA between subgroups of the enrolled patients and HCs.

Fig 1

(a) Comparison of plasma levels of HMGB1 between pAPS, APA+SLE, APS+SLE patients and HCs. (b) Comparison of plasma levels of HMGB1 between SLE patients with and without disease flares. (c) Comparison of plasma levels of sRAGE between pAPS, APA+SLE, APS+SLE patients and HCs. (d) Comparison of plasma levels of sRAGE between SLE patients with and without disease flares. P values of < 0.008 were regarded as statistically significant for multiple comparisons. APA, antiphospholipid antibody; HC, healthy control; HMGB1, high-mobility group box 1; pAPS, primary antiphospholipid syndrome; SLE, systemic lupus erythematosus; sRAGE, soluble receptor for advanced glycation end products.