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Scales represent dimension in cm. The kidney shape, size, and volume highly differ between the normal control (panel A: total kidney volume (TKV) = 591 ml) and the patients (panel B: TKV = 1327 ml; panel C: TKV = 3026 ml; panel D: TKV = 5836 ml). Kidneys were reconstructed using VMTK software based on binary masks obtained from ImageJ polyline manual tracings on representative CT images.
