Table 3. Inter and intra-rater reproducibility of single kidney volume (SKV) measured by expert and beginner operators using different quantification methods on MR and CT images from ADPKD patients in the experimental dataset.
| SKV computation method | Intra-rater (Expert) | Intra-rater (Beginner) | Inter-rater | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| SKV Difference ml |
SKV Difference % |
CV % |
SKV Difference ml |
SKV Difference % |
CV % |
SKV Difference ml |
SKV Difference % |
CV % |
||
| MR | ImageJ polyline | -4±24 | -0.4±2.4 | 1.18 | -12±84 | -3.3±18.3 | 4.04 | -28±50 | -2.5±4.7 | 2.77 |
| Osirix free-hand | -9±24 | -0.3±2.5 | 1.26 | 7±116 | 0.8±7.4 | 5.70 | -24±97 | -3.1±7.1 | 4.92 | |
| Livewire tool | -8±24 | -1.3±3.4 | 1.25 | 7±47 | -0.5±3.7 | 2.28 | -35±46 | -2.8±4.6 | 2.83 | |
| Stereology | 7±55 | 1.3±5.5 | 2.80 | 16±82 | 0.2±11 | 4.13 | -34±89 | -2.9±14.6 | 4.75 | |
| Mid-slice method | -20±60 | -2.2±7.7 | 3.11 | -13±115 | -0.8±5.1 | 5.48 | -62±252 | -11.3±29.8 | 12.61 | |
| Ellipsoid method | -23±146 | -3.8±25.3 | 8.46 | -101±367 | -19.1±46 | 21.06 | -0.79±242 | 0.1±31.9 | 17.73 | |
| CT | ImageJ polyline | 6±25 | 0.6±1.3 | 1.14 | -13±31 | -1.2±1.9 | 1.48 | -7±31 | -0.03±2.0 | 1.38 |
| Osirix free-hand | -8±19 | -0.5±1.3 | 0.89 | -0.1±27 | -0.3±2.0 | 1.19 | 7±20 | 0.7±1.6 | 0.95 | |
| Livewire tool | 10±21 | 0.7±1.1 | 1.05 | 5±19 | -0.2±1.9 | 0.88 | -12±25 | -0.8±1.6 | 1.23 | |
| Stereology | 15±35 | 0.4±2.9 | 1.69 | -9±24 | -1.2±3.0 | 1.07 | -87±66 | -5.6±3.9 | 4.77 | |
| Mid-slice method | 19±117 | 1.6±6.3 | 6.00 | -26±58 | -2.0±3.6 | 3.21 | 18±73 | 1.8±4.6 | 3.79 | |
| Ellipsoid method | -31±193 | -4.1±16.9 | 9.28 | 7±185 | 0.6±12.3 | 9.70 | 121±287 | 5.9±18.0 | 15.65 | |
Number of single kidneys analyzed n = 30 for MR and n = 30 for CT. Single Kidney Volume (SKV) difference is expressed as mean ± SD.
SKV Difference (ml) = Absolute difference between 1st and 2nd tracing; SKV Difference (%) = Percentage difference between 1st and 2nd tracing; CV = coefficient of variation for repeated measures.