Table 1. Experimental genotype-phenotype maps used in this study.

ID	genotype	organism	reference
I	scattered genomic mutations	E. coli	[19]
II	β-lactamase enzyme point mutations	E. coli	[1]
III	chromosomes combinations	A. niger	[30]
IV	scattered genomic mutations	E. coli	[28]
V	chromosomes combinations	A. niger	[30]
VI	envelope glycoprotein point mutations	HIV-1	[29]