Table 10:
GRADE Evidence Profile for Comparison of HBOT and Standard Care on Time to Heal
| Number of Studies (Design) | Risk of Bias | Inconsistency | Indirectness | Imprecision | Publication Bias | Upgrade Considerations | Quality |
|---|---|---|---|---|---|---|---|
| 1 (RCT) | No serious limitations | No serious limitations | No serious limitations | Very serious limitations (−2)a | Undetected | No other considerations | ⊕⊕ Low |
| 1 (NRCT)34 | No serious limitations | No serious limitations | No serious limitations | Very serious limitations (−2)a | Undetected | No other considerations | ⊕ Very Low |
Abbreviations: GRADE, Grading of Recommendations Assessment, Development, and Evaluation; HBOT, hyperbaric oxygen therapy; NRCT, nonrandomized controlled trial; RCT, randomized controlled trial.
a
The range of time to heal was quite wide. Median time would have been a more appropriate measure for time to heal.