. 2017 May 12;17(5):1–142.

Table 13:

Results of Economic Literature Review—Summary

Author, Year, Location	Study Design and Perspective	Population/Comparator	Interventions	Results
Author, Year, Location	Study Design and Perspective	Population/Comparator	Interventions	Health Outcomes	Costs	Cost-Effectiveness
Guo et al, 2003, United States⁴⁷	Cost–utility analysis Decision model 12-year model United States societal perspective	60-year-old patients with severe diabetic foot ulcers (Wagner grade 3 or higher)	HBOT Standard care	0.61 QALY gained per person for HBOT	Incremental cost of $1,371 per person for HBOT	$2,255/QALY
Chuck et al, 2008, Canada⁴⁸	Cost–utility analysis Decision model 12-year model Canadian provincial ministry of health	65-year-old patients with diabetic foot ulcers	HBOT Standard care	HBOT = 3.64 QALYs Standard care = 3.01 QALYs	HBOT = $40,695 Standard care = $49,786	HBOT dominates standard care

Abbreviations: HBOT, hyperbaric oxygen therapy; QALY, quality-adjusted life year.