Table 2:
Faglia et al, 199630 | Kalani et al, 200234,a | Abidia et al, 200328 | Kessler et al, 200331 | Duzgun et al, 200829 | Londahl et al, 201032 | Fedorko et al, 201635 | |
---|---|---|---|---|---|---|---|
Age ±SD (years) | 65.6 ± 9.1 | 65 ± 11 | 70 ± 6.6 | 67.6 ± 10.5 | 63.3 ± 9.15 | 68 (28–86)b | 62 ± 12 |
Male (%) | 64 | 86 | 50 | 69 | 54 | 84 | 70 |
Type of diabetes (%) | Not measured | ID: 43 NID: 57 | Not measured | 1: 15 2: 85 | Not measured | 1: 42 2: 58 | 1: 2 2: 98 |
Insulin therapy (%) | 66.7 | 43 | 63 | 92.3 | 90 | 91 | Not measured |
Average diabetes duration ± SD (years) | 19 ± 9 | 26 ± 17 | 10 ± 6.3 | 22.1 ± 13.1 | 15.88 ± 5.56 | 23 (3–54)c | 12.4 ± 10.0 |
Wagner grade (%) | 2: 15.2 | Not measured | 1: 12.5 | Not measured | 2: 12 | 2: 27 | 2: 42.6 |
3: 24.2 | 2: 87.5 | 3: 36 | 3: 62 | 3: 53.7 | |||
4: 60.6 | 4: 40 | 4: 11 | 4: 3.7 | ||||
Ulcer surface area ± SD (cm2) | Not measured | 4.49 ± 9.24 | 0.78 (0.18–8.66)d | 2.82 ± 2.43 | Not measured | 2.8 (0.6–39)d | 3.6 ± 5.7 (0.1–26.9)d |
Average ulcer duration (range) | Not measured | Not measured | 9 months (3–60 months) | Not measured | Not measured | 10 months (3–39 months) | 336 ± 528 days (28–3,650 days) |
TcPO2 of foot dorsum ± SD (mm Hg) | 21.29 ± 10.7 | Basale: 25 ± 10 During O2 inhalation: 185 ± 88 | 43 ± 19 | 45.2 ± 24.2 | Not measured | Not measured | Not measured |
Abbreviations: ID, insulin dependent; NID, not insulin dependent; O2, oxygen; SD, standard deviation; TcPO2, transcutaneous oxygen pressure.
Kalani et al34 was a nonrandomized controlled trial.
Age given with range, not ±SD.
Average diabetes duration given with range, not ± SD.
Ulcer surface area given with range.
Measured basal TcPO2 and TcPO2 during O2 inhalation.