Table 24:
Variables Varied in One-Way Sensitivity Analyses
| Variable | Value | Reference |
|---|---|---|
| Healed state to death state (sensitivity analysis 1) | 0.03–0.20 | Iversen et al66 |
| Healed state to death state (sensitivity analysis 2) | 0.083 | Chuck et al48 |
| Unhealed state to death state (sensitivity analysis 1) | 0.09–0.98 | Morbach et al67 |
| Unhealed state to death state (sensitivity analysis 2) | 0.083 | Chuck et al48 |
| Major lower leg amputation state to death state (sensitivity analysis 1) | 0.28–0.48 | Jones et al68 |
| Major lower leg amputation state to death state (sensitivity analysis 2) | 0.133 in first year 0.083 in other years | Chuck et al48 |
| Minor lower leg amputation state to death state (sensitivity analysis 2) | 0.083 | Chuck et al48 |
| Healed state to unhealed state (sensitivity analysis) | 0.07–0.35 | Waaijman et al69 |
| Major lower leg amputation (sensitivity analysis 1) | HBOT: 0.01–0.09 SC: 0.01–0.33 | Faglia et al30 (1st year) Hopkins et al51 (2nd and 3rd years) |
| Major lower leg amputation (sensitivity analysis 2) | HBOT: 0.01–0.11 SC: 0.001–0.01 | Abidia et al28 (1st year) Hopkins et al51 (2nd and 3rd years) |
| Major lower leg amputation (sensitivity analysis 3) | HBOT: 0.01–0.08 SC: 0.01–0.10 | Londahl et al32 Hopkins et al51 (1st to 3rd years) |
| Major lower leg amputation (sensitivity analysis 4) | HBOT: 0.01–0.02 SC: 0.02–0.08 | Morbach et al67 |
| Minor lower leg amputation (sensitivity analysis 1) | HBOT: 0.02–0.60 SC: 0.02–0.36 | Faglia et al30 (1st year) Hopkins et al51 (2nd and 3rd years) |
| Minor lower leg amputation (sensitivity analysis 2) | HBOT: 0.02–0.11 SC: 0–0.02 | Abidia et al28 (1st year) Hopkins et al51 (2nd and 3rd years) |
| Minor lower leg amputation (sensitivity analysis 3) | HBOT: 0.02–0.08 SC: 0.02–0.10 | Londahl et al32 Hopkins et al51 (1st to 3rd years) |
| Diabetic foot ulcer healing, with 3-year data (sensitivity analysis 1) | HBOT: 0.25–0.52 SC: 0.13–0.29 | Londahl et al32 Kalani et al34 |
| Diabetic foot ulcer healing, first year (sensitivity analysis 2) | HBOT: 0.63 SC: 0 | Abidia et al28 |
| Utility values | 0.84–0.68 | Redekop et al70 |
| Utility values for standard care | 0.76 | O'Reilly et al71 |
| Per-session physician cost for HBOT (physician in chamber with patient) | $356.20 | Ontario Schedule of Benefits for Physician Services60 |
| Per-session physician cost for HBOT (physician in the HBOT facility and available if necessary) | $35.75 | Ontario Schedule of Benefits for Physician Services60 |
| Number of HBOT sessions | 40 | Expert opinion |
| Physician cost billed as minor assessment | $273.05 | Ontario schedule of benefits for physician services,60 expert opinion |
Abbreviations: HBOT, hyperbaric oxygen therapy; SC, standard care.